AMPROVET 20% WSP

DESCRIPTION

Amprolium is a coccidiostat (antiprotozoal) used for the treatment and prevention of coccidiosis in calves, sheep, goats, chickens (broilers and breeders) and other fowl such as turkeys, with activity against Eimeria spp., especially Eimeria tenella, E. acervuline, E. praecox and Eimeria necatrix. It is a thiamine (vitamin B1) analogue, and its pharmacological effect relies on competitive inhibition of thiamine uptake.

Amprolium competitively inhibits the active transport of thiamine in isolated second-generation schizonts of Eimeria spp. and in host intestinal cells. Upon ingestion of amprolium, the coccidia experience thiamine deficiency and starve from malnutrition.

 

INDICATIONS

AMPROVET 20% WSP It is used as a preventive or therapeutic agent against Eimeria infections in poultry, especially E. tenella, E. necatrix, E. acervulina and E. praecox.. It is effective against other protozoal infections like Histomoniasis (Blackhead) in turkeys and poultry; against coccidiosis in calves, sheep and goats; against amaebiasis in various species.

 

CONTRA-INDICATIONS

Do not use in layers producing eggs for human consumption.

Do not administer to animals with impaired hepatic and/or renal functions.

Do not administer to turkeys before the age of 8 to 10 weeks.

 

SIDE EFFECTS

High doses may result in delayed growth in broilers or polyneuritis.

Long-term administration of amprolium in high doses may result in thiamine (vitamin B1) deficiency in the host.

 

DOSAGE AND ADMINISTRATION

For oral administration

Calves, sheep and goats:

     Preventive                  : 1 g per 40 kg body weight through drinking water or milk for 21 days.

     Curative                      : 1 g per 20 kg body weight through drinking water or milk for 5 days.

Poultry :

       Preventive                : 1 kg per 2,000 liters of drinking water for 1 - 2 weeks.

       Curative                    : 1 kg per 700 liters of drinking water for 5 - 7 days.

Mixed with milk replacer use the product within 12 hours. Mixed with drinking water use the product within 24 hours.

 

WITHDRAWAL PERIOD  

Meat:

Calves, goats, sheep:           3 days

Poultry                                   3 days

 

STORAGE

Store in a dry and dark place between 8 °C and 25 °C.

Store in closed packing.

Keep away from children.

 

PACKING

Jar of 1,000 g (12 jars per box).