Contains per g:
Amoxycillin trihydrate 200 mg
Colistin sulphate 1,000,000 IU
The combination of amoxycillin and colistin acts synergically. Amoxycillin is a semi-synthetic penicillin with a broad antimicrobial activity against both Gram-positive and Gram-negative bacteria. The spectrum of amoxycillin includes: Campylobacter, penicillinase-negative Staphylococcus and Streptococcus, spp., Bacillus anthracis, Corynebacterium spp., Clostridium spp., Brucella spp., Haemophilus spp., Pasteurella spp., Salmonella spp., Moraxella spp., E. coli, Erysipelothrix rhusiopathiae, Fusiformis, Bordetella spp., Diplococci, Micrococci and Sphaerophorus necrophorus. The bactericidal action is due to inhibition of cell wall synthesis. The excretion takes mainly place via the urine and the bile and this makes amoxycillin useful for the treatment of renal infections and Salmonella infections in the intra-hepatic biliary tree. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Colistin acts by disrupting the bacterial cell membrane
with leakage of intracellular materials and it inhibits bacterial oxidative metabolism. Susceptible bacteria are t strains of Escherichia coli, Pseudomonas aeruginosa, Salmonella spp., Haemophilus spp., Shigella spp., Pasteurella
spp., Brucella spp., Aerobacter aerogenes and Bordetella bronchiseptica. Colistin sulphate is hardly absorbed after oral administration (less than 1 % of the administered dose) and therefore remains active only in the gastrointestinal tract.
VETKO AMOXY-COL WSP is indicated for treatment and prevention of gastrointestinal infections, respiratory infections, urogenital infections, local inflammations and secondary bacterial infections during viral diseases in calves, pigs, lambs and poultry. The product is also indicated in case of infections caused by bacteria susceptible to colistin, especially Colibacillosis and Salmonellosis.
Do not administer to animals hypersensitive to amoxicillin and/or colistin. Do not administer to animals with a seriously impaired renal function. Do not administer concurrently with tetracyclines, fluorophenol, macrolides and lincosamides. Do not administer to animals with an active microbial digestion. Do not use in layers producing eggs for human consumption.
DOSAGE AND ADMINISTRATION
For oral administration via feed or drinking water.
Poultry, pigs : 100 g per 150 liters of drinking water for 3 - 5 days.
Calves, lambs : 5 g per 50 kg bodyweight for 3 - 5 days.
Mixed with feed, use the product immediately. Mixed with drinking water, use the product within 24 hours.
Meat : 8 days
Store in a dry and dark place between 8 °C and 25 °C.
Store in closed packing.
Keep away from children.
Sachet of 100 g (120 sachets per box).
Jar of 1,000 g (12 jars per box).